The Agathocleous lab is interested in stem cell metabolism and how it compares to the metabolism of cancers from the same tissue.
The DeBerardinis lab seeks to characterize metabolic disorders, understand how they compromise tissue function, and design therapies to restore normal metabolism.
The Hoxhaj lab seeks to understand the molecular mechanisms that control cellular metabolism to reveal new therapeutic strategies for cancer and other metabolic disorders.
The McBrayer lab studies the metabolic mechanisms that influence the development of gliomas with a particular focus on identifying metabolic vulnerabilities that may reveal new therapeutic strategies.
The Mishra lab studies how mitochondria regulate normal cellular function and develops mouse models to better understand mitochondrial diseases.
The Morrison lab studies the mechanisms that regulate stem cell function and the ways in which cancer cells hijack these mechanisms to enable tumor formation.
The Xu lab studies how gene regulation controls stem cell function in the blood forming system and the development of childhood leukemia.
The Zhu lab is identifying the mechanisms that regulate liver regeneration and how these mechanisms influence the development of hepatocellular carcinoma.
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